Mo1115 – Pro-Inflammatory and Pro-Fibrotic Stem Cell Variants in Crohn’s Disease
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چکیده
منابع مشابه
The pro-fibrotic and anti-inflammatory foam cell macrophage paradox.
The formation of foamy macrophages by sequestering extracellular modified lipids is a key event in atherosclerosis. However, there is controversy about the effects of lipid loading on macrophage phenotype, with in vitro evidence suggesting either pro- or anti-inflammatory consequences. To investigate this in vivo we compared the transcriptomes of foamy and non-foamy macrophages that accumulate ...
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Inflammatory bowel disease (IBD) is an irregular response of immune system accompanied with different inflammatory manifestations including alterations in cytokines. Probiotics are non-pathogenic organisms with probable effects in various conditions such as inflammation. The present study hypothesized whether oral intake of bifidobacterium and lactobacillus in form of probiotic yogurt may ...
متن کاملProbiotic yogurt Affects Pro- and Anti-inflammatory Factors in Patients with Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is an irregular response of immune system accompanied with different inflammatory manifestations including alterations in cytokines. Probiotics are non-pathogenic organisms with probable effects in various conditions such as inflammation. The present study hypothesized whether oral intake of bifidobacterium and lactobacillus in form of probiotic yogurt may ...
متن کاملPro-fibrotic SNPs
Staphylococcus aureus stifles its host's immune response by producing an immunosuppressive molecule, report Thammavongsa and colleagues. The new study reveals that without the cell wall enzyme adenosine synthase A (AdsA), most staphylococci fail to thrive and cause severe disease in mice. The gene encoding AdsA contains a 5 Ј-nucleotidase domain, making it similar to a family of mammalian enzym...
متن کاملMalondialdehyde-acetaldehyde (MAA) modified proteins induce pro-inflammatory and pro-fibrotic responses by liver endothelial cells
Introduction Recent reports have implicated liver non-parenchymal cells in liver injury as they can secrete; pro-inflammatory cytokines, excessive matrix proteins during fibrosis, and have been shown to initiate local immune responses [13]. Of the non-parenchymal cells, sinusoidal liver endothelial cells (SLECs) have been suggested to be a major contributor to the inflammatory processes observe...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2019
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(19)38712-8